In case 6 (fetal cleft lip and palate, right kidney cystic hypoplasia, bilateral foot fissure, lateral toe, and abnormal hand development), the fetus carried a mutation in the TP63 gene, which was correlated to ectrodactyly, ectoderm dysplasia, and cleft lip/palate syndrome-3 (EEC3). This evidence concerns the gene TP63 and oral cavity neoplasm.