There was a dramatic decrease in the migration of PCa cells in the miR‐539 mimic group and the si‐DLX1 group in comparison to the blank and NC groups (P < 0.05), while it drastically increased in the miR‐539 inhibitor group (P < 0.05) and there was no significant difference in the inhibitor + si‐DLX1 group (P > 0.05). This evidence concerns the gene DLX1 and posterior cortical atrophy.