For example, miR‐107 could function as a tumor suppressor gene in esophageal carcinoma,18 lung cancer19 and hepatocellular carcinoma,20 whereas act as an oncogene in liver cancer21 and colorectal cancer.6 However, studies have shown that miR‐107 may play different or even opposite roles in the same cancer. This evidence concerns the gene ENSG00000280371 and hepatocellular carcinoma.