LncRNAs are involved in many cellular processes like cell proliferation, migration and invasion.25 HOTAIR expression is also enhanced in non‐small‐cell lung cancer (NSCLC) and knockdown of HOTAIR suppresses NSCLC cell invasion and metastasis.26 Additionally, overexpression of HOTAIR can be referred to as a biomarker in gastric cancer (GC) and silenced HOTAIR could inhibit the cell invasion and viability in GC.13 Here, HOTAIR is linked to non-small cell lung carcinoma.