CD8A and B-cell non-Hodgkin lymphoma: Consistent with this finding, in a mouse model of tumor dormancy, the depletion of the CD8+ T cells was significantly associated with decreased duration of dormancy and shortened mean time for B cell lymphoma recurrence on the spleen, showing that CD8+ T cells contributed to the induction and maintenance of the state of dormancy via production of IFN-γ (21).