CAV1 and neoplasm: Moreover, multivariate Cox regression analyses revealed that the presence of BM (P < 0.001, hazard ratio [HR] 0.181, 95% confidence index [CI] 0.124–0.264), non-SQC type (P = 0.007, HR 1.762, 95% CI 1.168–2.659), and Cav-1 expression in tumor cells (P = 0.005, HR 1.715, 95% CI 1.175–2.502) were independent prognostic factors of OS.