DEAF1 and type 1 diabetes mellitus: Other variants found in clusters on SSC2 are located in or adjacenct to DEAF1 (8 intron variants, min p-value 3.47 × 10−29), which is a transcription factor that regulates proliferation of epithelial cells (Barker et al. 2008) and that forms a dominant-negative splice isoform in type 1 diabetes, which correlates with disease severity (Yip et al. 2015).