MYC and chronic myelogenous leukemia, BCR-ABL1 positive: This chronic myelogenous leukemia (CML) system (K562) is particularly interesting given the role of c-Myc in leukemia tumorigenesis and specifically in CML progression (Vaqué et al. 2005; Delgado and León 2010; Albajar et al. 2011).