Through an analysis of microarray data, we identified nine tumor suppressors, GADD45B, PMAIP1, XAF1, CYR61, IL24, ATF3, DLC1, RHOB and TNFAIP3, that were downregulated by TFAP2C overexpression in NSCLC cells. This evidence concerns the gene GADD45B and non-small cell lung carcinoma.