To elucidate a role of TFAP2C in NSCLC, we previously reported that TFAP2C mediates inhibition of A-kinase anchor protein 12 and activation of cell division protein kinase 6 through upregulation of miR-183 and downregulation of miR-33a, leading to cell cycle progression and NSCLC malignancy [7]. This evidence concerns the gene TFAP2C and non-small cell lung carcinoma.