TNFAIP3 and non-small cell lung carcinoma: The results of the present study have shown that TFAP2C can contribute to NSCLC tumorigenesis via downregulation of many tumor suppressors including GADD45B, PMAIP1, XAF1, CYR61, IL24, ATF3, DLC1, RHOB, and TNFAIP3.