Through an analysis of microarray data, we identified nine tumor suppressors, GADD45B, PMAIP1, XAF1, CYR61, IL24, ATF3, DLC1, RHOB and TNFAIP3, that were downregulated by TFAP2C overexpression in NSCLC cells. Here, CCN1 is linked to non-small cell lung carcinoma.