LEF1 and neoplasm: Based on their tumor LEF1 and OV6 content, the patients were classified into 4 groups: group A, high OV6 and LEF1 intensity; group B, high OV6 but low LEF1 intensity; group C, high LEF1 but low OV6 intensity; and group D, low OV6 and LEF1 intensity (Fig. 1a).