Among the highest-scoring genes detected using the proposed method, it is suspected that STARD3, PGAP3, ORMDL3, PSMD3 and HAPLN3 are the biomarkers of the HER2 + subtype [26–31], thus indicating that FOXC1 can identify basal-like subtypes in hereditary breast cancer cohorts [32]. The gene discussed is HAPLN3; the disease is Hereditary breast cancer.