The in vivo test showed that behavioral improvements observed after the administration of NA-beer and its components in this study appear to be clearly associated with the in vitro results obtained from AChE and buthylcholinesterase (BChE) by our research group testing silicon in human neuroblastoma cells [128], suggesting that potential improvements in cholinesterase levels were involved and that silicon was one of the major factors responsible for this inhibition effect. The gene discussed is BCHE; the disease is neuroblastoma.