PROCR and malaria: This trend was also observed for other A-type variants not predicted to bind EPCR and possibly associated with rosetting (Mann-Whitney U test, p<0.001) with a median of 3.6 (range: 0–32.8) for malaria-naïve samples and median values of 0.1 (range: 0–4.4) and 0.0 (range: 0–1.6) for samples from ‘non-controller’ and ‘controller’ (Fig 3C).