This concept has been described already for systemic inflammation and sepsis,49, 50, 51, 52, 53, 54 DIC,55, 56 severe dengue fever,57 and after the infusion of desmopressin.58 Further research is needed to either consolidate or reject the hypothesis that the ADAMTS‐13/VWF ratio is superior to either factor for predicting VTE and survival in cancer patients. This evidence concerns the gene VWF and dengue disease.