TOR1A and Dystonia: This neurological disorder can also be inherited: the most prevalent and severe inherited dystonia (Weisheit et al., 2018), DYT1 dystonia, is caused by a loss-of-function mutation in the DYT1/TOR1A gene that deletes a single glutamic acid residue (ΔE302/303, or ΔE) from the encoded torsinA protein (Ozelius et al., 1997).