IL33 and asthma: Briefly, the following genes have been determined to have significant association with asthma susceptibility: the 17q21 locus with the ORMDL3 and GSDML genes, the IL33 gene on chromosome 9p24, the HLA- DR/DQ gene on chromosome 6p21, the IL1RL1/IL18R1gene on chromosome 2q12, the WDR36/ TSLP gene on chromosome 5q22 and the IL13gene on chromosome 5q31 (7).