Tissue damage by these intestinal helminths during feeding and migration results in production of danger associated molecular patterns and induce an immune response characterized by IgE secretion, IgG4 production, eosinophilia, production of Th2 cytokines (IL-4, IL-9, IL-10, IL-13) and induction of FOXP3+ regulatory T cells and the associated regulatory cytokines Tumor Growth Factor-β and IL-10. Here, IL10 is linked to Increased total eosinophil count.