To test the chemokine binding properties of these proteins, which specifically bound the anti-M3 1/27 antibody (Šebová et al., 2017), we chose two human chemokines: the inflammatory chemokine CCL5 suggested to be involved in melanoma and in tumor growth and progression (Aldinucci and Colombatti, 2014) and CXCL8, which is highly involved in wound healing and triggering the infiltration of both macrophages and neutrophils in cystic fibrosis (Raman et al., 2007) and is associated with a highly metastatic cancer phenotype (Liu et al., 2016). The gene discussed is CXCL8; the disease is melanoma.