TNFRSF10B and hepatocellular carcinoma: Dilshara et al. showed that CAPE (Caffeic acid phenethyl ester, 50 μM) significantly increased apoptosis (cell death) mediated by TRAIL (tumor necrosis factor-related apoptosis ligand inducer, 50 ng/ml) by positive regulation of DR5 (death receptor 5) mediated by CHOP (C / EBP family transcription factor) in Hep3B HCC cells.