CD19 and diffuse large B-cell lymphoma: Finally, another innovative and promising application of the molecular biology in DLBCL is that MRD can be employed as platform for immunotherapy: we know that anti-CD19 CAR-Ts offer to relapsed/refractory DLBCL patients an overall response rate (ORR) of 70%, 50% of CRs, and 60% of probability of surviving at 12 months (100).