To examine whether phosphorylated C/EBPα (induced by HA-mediated CD44v3-mediated PI3K-AKT activation) directly interacts with the promoter region of lncRNA UCA1, chromatin immunoprecipitation (ChIP) assays were performed in head and neck cancer cells with HA (or without HA). The gene discussed is AKT1; the disease is head and neck cancer.