Including fTr or fTr+QA booster dose had either no effects or suppressive effects on CD209+, MHCI+, and MHCII+ Mφ responses after TcG2/TcG4 vaccination and challenge infection (∧p < 0.05, Figures 4A,B), and CD80+ Mφ were significantly enhanced by fTr+QA booster immunization in challenged mice, suggesting an increase in B7-1 costimulatory signal for T cell activation. This evidence concerns the gene CD80 and infection.