Experimental murine studies and clinical correlation analyses have identified ligands for CXCR2 as major drivers of TAN recruitment into tumor lesions, involving CXCL1/KC, CXCL2/MIP-2, CXCL5/LIX, CXCL6, and MIF (12, 20–23). The gene discussed is CXCR2; the disease is neoplasm.