However, at 18 h after infection, there was a modest but significant reduction in the number of p62-positive autophagosomes in the MDM and plasma obtained post-AAT infusion compared to pre-AAT infused MDM + plasma (Figure 3B), indicating increased autophagosome maturation with M. intracellulare-infected post-AAT-infused MDM and plasma. Here, SERPINA1 is linked to infection.