SNHG12 and brain infarction: TTC staining showed that I/R treatment induced obvious infarcts in the brains of the rats (P < 0.01); however, MSC treatment significantly decreased the areas of the brain infarcts, and silencing of SNHG12 significantly enhanced the ameliorative effect of MSCs in reducing the infarct areas (all P < 0.05, Figure 5A).