The prognostic role of B7-H2 is not known in breast cancer and our result show that it may have positive prognostic role in curatively resected breast cancer patients.30 As previously noted, OX40 and OX40L is expressed on activated T cells.22 Expression of OX40 and OX40L may have a positive prognostic role as these may reflect presence of an activated T cells. The gene discussed is ICOSLG; the disease is breast cancer.