HLA-DQB1 and cranioectodermal dysplasia: The primary genes associated with CeD are Major Histocompatibility Complex class II (MHC-II) genes encoding HLA-DQ2 (i.e. HLA-DQA1*05 and HLA-DQB1*02) or HLA-DQ8 (i.e. HLA-DQA1*03 and HLA-DQB1*03:02).