Adamalysins genes/ A distintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family genes, ADAMTS1 (FC = −9.4, p = 0.009), and ADAMTS5 (FC = −5.7, p = 0.05) were significantly down-regulated in tumours, as compared to controls (Supplementary Table S16, Fig. 6). This evidence concerns the gene ADAMTS5 and neoplasm.