TP53 and systemic lupus erythematosus: The pathways associated with up-regulated genes include cell cycle, systemic lupus erythematosus, DNA Replication, ECM-receptor interaction, p53 signalling (Supplementary Table S5) while the pathways associated with down-regulated genes include leukocyte transendothelial migration, cell adhesion molecules, adherens junction, complement and coagulation cascade, PPAR signaling, circadian rhythm, focal adhesion, adipocytokine signaling pathway, and tight junction (Supplementary Table S6).