Among the top DEGs, up-regulated expression of genes such as COL10A1, MMP1, MMP11, and BUB1; down-regulated expression of genes such as ADH1B, CIDEC, FABP4, AQP7, RBP4, CDO1, FIGF, and LPL were reported to be differentially expressed in breast and or other cancers by various authors using microarray profiling in western population26–38, showing concordance with the present study. This evidence concerns the gene RBP4 and cancer.