AGS and STKM2 cells were infected with 5 MOI (multiplicity of Infection) of TFF1 adenovirus or control adenovirus for 48 h and stimulated or not with IL6 for 30 min; 5 MOI of TFF1 was identified as the optimum dose, as shown in Supplementary Fig. 6a. This evidence concerns the gene IL6 and infection.