Viral transcriptome coverage from the AITL sample with high KSHV detection was similar to that observed from the KSHV-positive primary effusion lymphoma cell line BCP-1, with expression of the classic latency genes LANA and Kaposin (63, 64), as well as expression of the viral interleukin-6 (IL-6) and IL-8 homologues (65, 66) and the viral E3 ubiquitin ligase (67) (Fig. 3). The gene discussed is CXCL8; the disease is primary effusion lymphoma.