PTBP3 and colorectal carcinoma: In multivariate Cox regression analysis, we also found that PTBP3 expression was also an independent prognostic marker for both OS (HR 2.484, 95%CI 1.761 to 3.502, p < 0.001) and DFS (HR 4.830, 95%CI 2.763 to 8.445, p < 0.001) in patients with CRC (Additional file 2: Table S2).