DHRS2 and nasopharyngeal carcinoma: DHRS2 gene is localized in chromosome 14q11.2, a region with high-frequency heterozygous loss in many tumors, including nasopharyngeal carcinoma [19], gastrointestinal stromal tumors [20], mesothelioma [21], esophageal squamous cell carcinoma [22] and metastatic lung adenocarcinomas [23].