Patients of non-EuroCaucasian origin had a more severe diabetes phenotype than EuroCaucasians, as shown by higher HbA1c values (9.6% vs. 6.6%, p = 0.0001); more frequent symptoms of diabetes (44% vs. 10%, p < 10−4); and requirement for insulin therapy at diabetes diagnosis (42% vs. 13%, p = 0.0002). The gene discussed is INS; the disease is diabetes mellitus.