In addition, we discovered that erbB4 regulates the phosphorylation of two molecules—with-no-lysine kinase 1 (WNK1), a kinase that is phosphorylated at Thr60 by Akt [44], and heat shock protein 60 (HSP60)—that promote tumorigenesis in other cancer types. This evidence concerns the gene HSPD1 and cancer.