After adjusting for AML prognosis factors, DNMT3A R882 mutant allele ratio was marginally associated with poorer OS and DFS (HR = 1.029, 95% CI 0.998–1.061, P = 0.066 for OS; HR = 1.026, 95% CI 0.990–1.063, P = 0.159 for DFS, Table 5). The gene discussed is DNMT3A; the disease is acute myeloid leukemia.