DNMT3A and acute myeloid leukemia: Analysis with proportional hazards model indicated that DNMT3A R882 mutations were significantly and independently associated with inferior OS and DFS in AML patients (HR = 1.725, 95% CI 1.221–2.437, P = 0.002 for OS; HR = 1.694, 95% CI 1.114–2.577, P = 0.014 for DFS, Table 4).