Mutation in CACNA1A can lead to spinocerebellar ataxia (SCA) type 6 [SCA6 (MIM: 183086)], episodic ataxia type 2 (MIM: 108500), and familial hemiplegic migraine type 1 (MIM: 141500) [8, 9]. This evidence concerns the gene CACNA1A and familial or sporadic hemiplegic migraine.