It was proposed that the resulting disinhibition unmasked a circuit through which LTMR input is relayed through PKCγ cells and ultimately to lamina I. We find no evidence for changes in either the total inhibitory synaptic input to PKCγ cells or the number of inhibitory synaptic inputs derived from PV cells following peripheral nerve injury (see below), but we do find that the incidence of inhibitory inputs, including those derived from PV interneurons, is similar on both PKCγ cells and vertical cells and that inhibitory PV cell excitability is reduced following nerve injury. This evidence concerns the gene PRKCG and peripheral nerve injury.