SIRT1 and coronary artery disorder: Breitenstein et al.29measured sirtuin 1 mRNA levels in peripheral monocytes and Gorenne et al.28 measured sirtuin 1 mRNA andprotein expression amount in human carotid endarterectomy materials.28 While both of these studies founda negative association between atherosclerosis and sirtuin expression, Kilic etal.30 found that serumsirtuin 1 levels were higher in stable CAD patients than in the controlpatients.30