Among cancers cells shown to express functional EpoRs include human breast carcinoma (MCF-7), hepatoma (HepG2), osteosarcoma (U2–OS), cervical carcinoma (HeLa), VHL-deficient renal clear cell carcinoma (RCC4), colon carcinoma (HCT-116), and colon carcinoma (7860-WT and SW480) cell lines [12]. This evidence concerns the gene VHL and colon carcinoma.