In addition, the large sample size of more than 700 patients in the derivation cohort may have further improved the statistical power, compared to the previous study.22 Second, the easy‐to‐use graphical tool consists of variables routinely evaluated in clinics such as tumor size, tumor number, AFP level, PIVKA‐II level, lymphocyte count, albumin level, and presence of ascites. The gene discussed is AFP; the disease is neoplasm.