In the present study, AURKA and AURKB were pharmacologically targeted by reversine, a purine analogue that presents antineoplasic effects on multiple models of cancer26, including acute myeloid leukemia (AML)27, multiple myeloma16, and chronic myeloid leukemia (CML)21. Here, AURKA is linked to chronic myelogenous leukemia, BCR-ABL1 positive.