Uroplakins, which line the surface of human urothelium (44, 45), could be important for gonococcal infection in a way similar to that of the uropathogenic E. coli, where mannosyl-glycans of uroplakin Ia are bound by FimH, which mediates bacterial adherence to urothelial cells (15, 45). The gene discussed is UPK1A; the disease is bacterial sexually transmitted disease.