FUT4 and gonorrhea: There may be a preference for binding human blood group antigens by N. gonorrhoeae since the gonococcus has ∼10-fold higher affinity for binding Lewis Y and sialyl-Lewis X than for binding Lewis X and ∼6-fold higher affinity for blood groups B and O than for blood group A. However, no correlation has been reported between the “secretor” status or the blood group type of a person and their predisposition to gonococcal infection (32, 33).