Remarkably, IHC analysis showed that among BCL6B-negative GC patients, those with CD3-positive expression exhibited the poorest survival (median survival time = 15.0 months), whereas BCL6B-negative GC patients with CD3-negative expression showed marginally different survival with a median survival time of 48.5 months (Fig. 6d). The gene discussed is BCL6B; the disease is gastric cancer.