Based on the MYC, BCL2, and BCL6 rearrangements, DLBCL cell lines were determined to fall into either wild-type MYC (WT-MYC) seen in HBL-1 and U2932 cell lines; single MYC rearrangement with immunoglobulin commonly referred to as single hit (MYC/IG; SH) seen in Raji and Ramos Burkitt lymphoma cell lines; MYC rearrangement with BCL2 gene (MYC/BCL2; DHL) seen in OCILY1, OCILY10, SUDHL2, and DOHH2 cell lines; or MYC rearrangements with both BCL2 and BCL6 genes (MYC/BCL2/BCL6; THL) seen in only VAL cell line (Table 1). Here, MYC is linked to diffuse large B-cell lymphoma.