Knockdown of LAMP1 reversed the UBL4A-induced autophagy suppression, mesenchymal-to-epithelial transition (Fig. 6a-b), inhibiton of autophagic flux (Fig. 6e), inhibition of cancer cell migration and invasion (Fig. 7a-c), cell proliferation (Fig. 7g) and wound healing capacity (Fig. 7j). The gene discussed is LAMP1; the disease is cancer.