Immunohistochemistry did not confirm TRPC3 expression patterns in PTEC mRNA profiling, revealing negative TRPC3 staining in ECs in all normal areas (n = 10/10 patients) (Figure 2aci), but only one tumor area (n = 1/10) showed faint positive TRPC3 staining in ECs (Figure 2acii). The gene discussed is TRPC3; the disease is neoplasm.