While higher inflammatory activity was observed in postmenopausal women compared to premenopausal women in this and other investigations (e.g., [17, 56]), a large longitudinal study assessing cardiovascular disease risk markers in women before and across menopause transition stages found no differences in CRP between premenopausal, perimenopausal, and postmenopausal women [93]. This evidence concerns the gene CRP and cardiovascular disorder.