Using online algorithms, we were able to predict potential miR-361 target genes involved in cancer metastasis, such as MEF2D [20], ROCK1 [21] and WNT7A [22], and the tumor microenvironment, including KPNA4 [23], PDE4B [24] and VEGF-A (Fig. 5a). This evidence concerns the gene PDE4B and neoplasm.