MEF2D and neoplasm: We found that miR-361 expression knockdown significantly reversed the NEAT1-specific shRNA-mediated decreases in tumor volume and weight and increased MEF2D, ROCK1, WNT7A, KPNA4, VEGF-A and STAT3 levels in mouse tumor samples (Fig. 7d-f), further validating that miR-361 functions downstream of NEAT1 to mediate the functions of NEAT1 in aggressive EC progression.