NFATC1 and cancer: GSEA of the involvement of FCN DE genes in hallmark cancer pathways uncovered the K-RAS-, Hedgehog-, and WNT/B-Catenin-signaling pathways as well as glycolysis signaling among the 11 significantly activated oncogenic pathways that were specifically recruited through the cooperation of NFATC1 and FLT3ITD in FCN stem cells (Fig. 5b, c).