On the other hand, treatment with SDF-1-pretreated ERCs remarkably attenuated the severity of experimental colitis and bloody stool (Fig. 3b, compared to the untreated group, D8: p < 0.001; D10: p < 0.001), as well as protected the length of the colon (Fig. 3c, d, compared to the untreated group, p < 0.001). This evidence concerns the gene CXCL12 and colitis.